Abstract

This study investigated the solubilization of valdecoxib in aqueous solutions of glycerol, propylene glycol, and poly(ethylene glycol) 400 at (298.15, 303.15, and 308.15) K. The analysis of valdecoxib was carried out by UV spectral measurements at λ max of 204 nm. The solubility of valdecoxib increased with increasing mass fraction of glycerol, propylene glycol, and poly(ethylene glycol) 400 at (298.15, 303.15, and 308.15) K. For poly(ethylene glycol) 400 + water mixtures, the solubility of valdecoxib was higher when compared to the glycerol + water and propylene glycol + water mixtures. The solubilization power of glycerol, propylene glycol, and poly(ethylene glycol) 400 at (298.15, 303.15, and 308.15) K was 1.1, 1.5, and 1.8; 2.6, 2.8, and 2.9; and 3.0, 3.5, and 3.9, respectively.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.