Abstract
Solitary renal metastasis of esophageal cancer is rare clinically, with only 14 cases being reported in the literature. The authors here report a case of a 53-year-old man with a metachronous hypopharyngeal and esophageal squamous cell carcinoma who developed a solitary renal metastasis after complete chemoradiotherapy for esophageal cancer, and subsequently received a left nephrectomy. The metastatic esophageal cancer was indistinguishable from primary renal neoplasm in the computed tomography but showed the histopathologic characteristic of esophageal cancer in directly invading the renal artery, and the tumor spreading in the kidney. The patient died of pneumonia two months after diagnosis. Among the previous 14 reported cases, 12 occurred in Asians, and their overall survival time ranges from two months to nine years after nephrectomy, either with or without adjuvant chemotherapy. Accordingly, a solitary renal mass in patients with a history of esophageal cancer is warranted to differentiate metastatic esophageal cancer from primary renal neoplasm, and a reliable therapy needs to be planned early for improving the patient’s chance of survival.
Highlights
Esophageal cancer is the sixth leading cause of cancer deaths worldwide, accounting for 406,800 cancer deaths in 2011 [1]
The authors report a case of metastatic esophageal squamous cell carcinoma to the kidney mimicking primary renal neoplasm in the computed tomography
Metastatic carcinoma of the kidney often appears as a solitary tumor or multiple subcapsular tumors infiltrating the renal parenchyma in Computed tomography (CT) [4]
Summary
Esophageal cancer is the sixth leading cause of cancer deaths worldwide, accounting for 406,800 cancer deaths in 2011 [1]. Most patients with esophageal cancer die from recurrence or metastasis, with the 5-year survival rate ranging from 15% to 25% [2]. The most common sites of metastasis are the liver, lungs, bones, and adrenal glands [3]. A unilateral renal metastasis is extremely rare. The authors report a case of metastatic esophageal squamous cell carcinoma to the kidney mimicking primary renal neoplasm in the computed tomography
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
