Abstract

Solitary plasmacytoma (SP), histologically indistinguishable from multiple myeloma (MM), is a kind of malignant tumor characterized by the proliferation of monoclonal plasma cells. SP is an independent subtype of plasmacytoma, including extramedullary plasmacytoma and solitary plasmacytoma of bone (SPB) [1]. Most solitary plasmacytomas progress to MM, and are usually treated in the department of hematology. SPB may involve in any bone, however, it mainly occurs in the axial skeleton, especially in a vertebra. SPB has a high risk of progression to MM, and on magnetic resonance imaging (MRI) examination, at least 25% of patients with an apparent solitary lesion have evidence of disease elsewhere.

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