Abstract
Isolated or solitary neurofibromas of the paranasal sinuses are rare. Mostly, they involve the maxillary sinus and so far, a solitary neurofibroma of the frontal sinus has never been reported in the literature. We present a case of frontal sinus neurofibroma treated successfully with surgical excision. A 28-year-old male presented with forehead swelling and computed tomography images revealed a tumor involving the left frontal sinus. Histopathological examination showed the tumor to be a neurofibroma. We discuss the clinical and pathological characteristics of neurofibroma arising in the nasal cavity and paranasal sinuses.
Highlights
Neurofibromas are benign nerve sheath tumors that originate from the peripheral nervous system
Neurofibromas can be categorized into dermal and plexiform subtypes. The former subtype is usually associated with a lone peripheral nerve in the integumentary system, while plexiform tumors are associated with many nerve bundles and can originate internally
We describe a case of a solitary neurofibroma arising from the frontal sinus
Summary
Neurofibromas are benign nerve sheath tumors that originate from the peripheral nervous system. They arise from the nonmyelinating Schwann cells but are commonly referred to as schwannomas in the literature [1]. Neurofibromas can be categorized into dermal and plexiform subtypes The former subtype is usually associated with a lone peripheral nerve in the integumentary system, while plexiform tumors are associated with many nerve bundles and can originate internally. An isolated neurofibroma can transpire without being associated with neurofibromatosis These solitary tumors tend to occur in the gastrointestinal system [3, 4], and very rarely they have been reported to occur in the paranasal sinuses. To the authors’ knowledge, no such case has been published to date
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