Solitary Metachronous Metastasis of Renal Cell Carcinoma to the Ureter

Kwun-Chung Cheng,Kin-Mam Lam,Hing-Sing So,Lysander Chau,Chak-Lam Cho

doi:10.5171/2013.854413

Kwun-Chung Cheng, Kin-Mam Lam + Show 3 more

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https://doi.org/10.5171/2013.854413

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Abstract

Renal cell carcinoma is well known for its varied presentation and its potential of metastasizing to virtually any organs. Metastasis to the ureter or bladder is extremely rare. To date only 52 cases of metastatic renal cell carcinoma to ureter have been reported. We report a case of metachronous solitary metastasis of renal cell carcinoma to the ipsilateral ureteric stump one year after radical nephrectomy of the primary tumour. Completion ureterectomy and partial cystectomy was performed and pathology confirmed metastatic renal cell carcinoma. Six months later the patient was found to have bladder recurrence again. Contrast computed tomography scan of abdomen showed multiple liver metastases. The disease progressed despite use of target therapy. He finally succumbed 29 months after the initial nephrectomy.

Highlights

We report a case of metachronous solitary metastasis of renal cell carcinoma to the ipsilateral ureteric stump one year after radical nephrectomy of the primary tumour
We report a case of metachronous metastasis of renal cell carcinoma to ipsilateral ureteric stump after radical nephrectomy
53 cases have been reported worldwide including our case. (Chiu KY et al, 2001; Esrig D et al, 1994; Kamota S et al, 2003; Leonard AM et al, 1996; Pearce I et al, 2000; Zorn KC et al, 2006) 43 cases occurred in ipsilateral ureteric stump and 10 cases occurred in contralateral ureter

Summary

Introduction

CaseRenal cell carcinoma with metastasis to ureter is extremely rare. We report a case of metachronous metastasis of renal cell carcinoma to ipsilateral ureteric stump after radical nephrectomy. To date only 52 cases of metastatic renal cell carcinoma to ureter have been reported. We report a case of metachronous solitary metastasis of renal cell carcinoma to the ipsilateral ureteric stump one year after radical nephrectomy of the primary tumour. Completion ureterectomy and partial cystectomy was performed and pathology confirmed metastatic renal cell carcinoma.

Results

Conclusion