Solitary Melanoma of the Central Nervous System

Abstract

Primary melanoma of the central nervous system (CNS) is a rare entity, thus the diagnostic and therapeutic experience is based on a limited number of published cases. The diagnostic dilemma of solitary CNS melanoma is whether it is primary. Primary CNS malignant melanoma has more favorable prognosis than metastatic disease according to the published reports in the literature. Primary melanoma of the CNS may occur as intra-axial or extra-axial mass lesions or may be presented as meningeal spread. We describe the clinical features of 23-year-old male patient with solitary cerebral melanoma, including magnetic resonance imaging and histopathologic findings in light of literature.