Abstract
AbstractThe easy accessible building units 5‐O‐(2,3,4,6‐tetra‐O‐benzoyl‐α‐D‐mannopyranosyl)penyl 2‐cyanoethyl N,N‐diisopropylphosphoramidite (9) and 2,2‐bis(4,4′‐dimethoxytrityloxymethyl)propyl 2‐cyanoethyl N,N‐diisopropylphosphoramidite (12) were used for the sequential elongation of immobilized tetrametric thymidylic acid according to a DNA synthesis protocol. Ammonolysis of the individual immobilized adducts led to the isolation of the target compounds 1 and 2.
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