Abstract

Solid pseudopapillary neoplasms (SPMs) of the pancreas are extremely rare tumors of the pancreas that typically affect young women and have a favorable prognosis. Herein, we report a 25-year-old female with solid pseudopapillary tumor of the pancreas who presented with atypical epigastric pain. The patient underwent pancreatoduodenectomy (Whipple procedure). She remained asymptomatic and showed no signs of disease after one year of follow-up. This type of pancreatic tumors is amenable to cure after complete surgical resection, even in cases with capsular invasion, unlike any other malignant tumors of the pancreas.

Highlights

  • Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor of the pancreas with low malignant potential that typically affects young women in their third decade of life

  • The typical image in computed tomography (CT) or magnetic resonance (MR) is a mass that consists of both solid and cystic elements surrounded by a well-defined capsule

  • Solid pseudopapillary tumor of the pancreas is an extremely rare neoplasm of the pancreas. It represents approximately 1% of all the tumors of the pancreas. It was first described in 1959 by Frantz, and many different names were given to these neoplasms until 1996 that WHO categorized those neoplasms as solid pseudopapillary tumors of the pancreas [7]

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Summary

Introduction

Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor of the pancreas with low malignant potential that typically affects young women in their third decade of life. The typical image in computed tomography (CT) or magnetic resonance (MR) is a mass that consists of both solid and cystic elements surrounded by a well-defined capsule These neoplasms can be misdiagnosed as adenocarcinoma of the pancreas [5]. A magnetic resonance scan was performed that described a mass in the head of the pancreas measuring 2.8 cm x 2.8 cm x 2.5 cm with well-defined borders and mild contrast enhancement (Figure 2). The second focal change in the genome was described in the expression of neurofibromin 1 (NF1) protein in exon 49 that it is not expected to cause any abnormal expression in the function and structure of protein NF1 The findings of this genetic test were not conclusive, and no genetic background was recognized for the expression of this pancreatic neoplasm

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European Study Group on Cystic Tumours of the Pancreas
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