Abstract
A trialkoxy-diphenyl-methylester and amide linkage for solid-phase peptide synthesis with Fmoc strategy is described. Protected peptide esters can be smoothly cleaved with weak acid, resulting in fragments with intact side-chain protection. Mild acidic cleavage of the corresponding peptide amide resins yields peptide amides.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have