Abstract

AbstractA facile solid phase. synthesis of 2‐substituted1,3‐oxazin‐6‐ones using polymer‐supported Meldrum's acid has been reported. Reaction of the resin‐bound cyclic malonic acid ester with triethyl orthoformate and subsequent double substitution with amide, afforded the corresponding polymer‐supported acylaminomethylene cyclic malonic acid ester, which upon thermal treatment led to1, 3‐oxazin‐6‐ones in good yields and with high purity.

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