Abstract
We review the use of the solid phase synthesis methodology for the preparation of diverse and potent MRI probes.
Highlights
The invention and development of imaging techniques such as magnetic resonance imaging, positron emission tomography, single-photon emission computed tomography, computedLiam Connah and Goran AngelovskiLiam Connah received his MChem degree from the University of Hull
MRI has emerged as a very important tool in biomedical research and is an essential diagnostic method in clinical radiology today. It can be utilised as a standalone technique, the inherent low sensitivity of the method has led to the development of contrast agents (CAs) in order to improve the specificity of the measurement
To expand on the elegance of the Solid phase synthesis (SPS) methodology and its application potential, this review aims to provide a concise overview of the strategies employed in the development of MRI CAs using it and evaluate the outlook of the approach in future CA synthesis
Summary
Liam Connah received his MChem degree from the University of Hull Afterwards he moved to the Max Planck institute for Biological Cybernetics where he completed his PhD. Dr Angelovski has been recently appointed to lead the Laboratory of Molecular and Cellular Neuroimaging of the newly established Center for Excellence in Brain Science and Intelligence Technology (CEBSIT) of the Chinese Academy of Sciences (CAS) in Shanghai. There he is going to continue his research on the development and in vivo utilisation of bioresponsive MRI contrast agents
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
