Abstract
In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great attention as colloidal drug delivery systems for incorporating hydrophilic or lipophilic drugs and various macromolecules as well as proteins and nucleic acids. Therefore, SLNs offer great promise for controlled and site specific drug and gene delivery. This article includes general information about SLN structures and properties, production procedures, characterization. In addition, recent progress on development of drug and gene delivery systems using SLNs was reviewed.
Highlights
Nanotechnological sciences brought considerable progresses in the diagnosis and treatment of disease
In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems
This review presents the preparation and characterization methods of SLNs and the recent advances in application of them as drug/gene delivery system are discussed in more details
Summary
Nanotechnological sciences brought considerable progresses in the diagnosis and treatment of disease.
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