Abstract

An unending challenge in pharmaceutical industry is related to poor solubility of maximum drugs To overcome this problem various technologies have been developed but none appears to be a promising one Solid dispersion is a solubilization technology emphasizing basically on drug polymer two component systems in which drug dispersion and its stabilization is the key for formulation development Therefore this technology has been realized as extremely useful tool in improving the dissolution properties of poorly water soluble drugs and in recent years a great deal of knowledge has been accumulated about solid dispersion but their commercial application is limited This review summarizes our current understanding of various methods used for the preparation of solid dispersions emphasizing the elementary aspects of this significant technology

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