Solid Dispersion as a Novel approach in Pharmaceuticals

Abstract

To improve the dissolution rate and bioavailability of poor water soluble drugs, solid dispersion is an effective way. There are also many other methods but solid dispersion method emerged out promising in context to improving solubility of the drug. Generally, the hydrophilic matrix and a hydrophobic drug constitutes the group of solid products that forms solid dispersion. This review article focuses on the preparation methods, solubility enhancement, evaluation parameters, carriers used, limitations, advantages , disadvantages and applications of solid dispersions. This article also focuses the market based products of solid dispersion.