Abstract
Background: Before the weaning phase, piglets often experience diarrhea and anemia caused by infection with germs such that after weaning, their growth rate reduces, they become pale and also prone to other illnesses which may lead to death. This study aims to determine the effect of earthworm flour (TCT) on growth, morbidity, mortality, blood profile, and antibody titer as an immunomodulator. Method: Ninety piglets were used before weaning which was divided into four groups, each consisting of 18 members, namely the group that was not given TCT as a control (P0), the one that was given TCT from the age of 20 to 50 (for 30 days total) days with a concentration of 1% in the feed (P1), the concentration of 1.5% (P2), the concentration of 2% (3) and concentration of 2.5% (4 ). At 14 days old, Hog Cholera vaccination was administered by intramuscular injection, and it was repeated at the age of 28 days. Bodyweight was weighed at the beginning of the study, which was at 21 days old, then repeated at 28, 35, 42, 49 and 60 days after treatment to determine performance. Morbidity and mortality were observed from 21 to 60 days old. At 50 days, blood was collected and stored in a vacuum tube containing an anticoagulant (EDTA) for profile examination. The Hog Cholera antibody titer assessment was performed using the ELISA method. Result: The TCT concentration of 1.5% in piglet feed significantly increased body weight, decreased morbidity, prevented morbidity, elevated WBC, RBC, Hb, PCV, and neutrophils, reduced eosinophils and lymphocytes but still within a normal range. Therefore, it is judged that the preparation of 1.5% is effective and safe, and the % CP value of hog cholera is positive with a rate of 72.9%, which is significantly higher than the control (66.64%). Conclusion: Earthworm flour with a concentration of 1.5% in feed is harmless, potent in increasing body weight and is indicated as an immunomodulator.
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