Abstract

Introduction: Maternal deaths are defined by the WHO as the death of a woman while she is pregnant or within 42 days of termination of pregnancy, irrespective of the duration and the site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes. The Sequential Organ Failure Assessment (SOFA) score is one of the tools to evaluate the degree of organ failure in the patients leading to morbidity or mortality. Aims and Objectives: To validate that SOFA score can be used to know the prognosis of patients in obstetric ICU and to decide treatment accordingly. Materials and Methods: Organ failure was evaluated according to the maximum score for each one of its six components and the total SOFA score was calculated. The study was conducted in the Dept of Obstetrics and Gynaecology, Medical college and SSG Hospital, Baroda from 1st September 2017 to 31st August 2018. Result: The SOFA score trend in the patients who recovered showed a significant decrease with respect to time whereas the SOFA score trend in the patients who expired showed a significant increase. Interpretation of the area under the ROC curve showed that the performance of the total maximum SOFA score was excellent (AUC 0.972; 95% CI: 0.917 to 0.995). Conclusion: Total SOFA score proved to be an effective tool for evaluating the severity and estimating prognosis in obstetric ICU.

Highlights

  • Maternal deaths are defined by the WHO as the death of a woman while she is pregnant or within 42 days of termination of pregnancy, irrespective of the duration and the site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes

  • Sequential Organ Failure Assessment (SOFA) score was calculated at the time of admission, 12 hrs 4after admission and every 24 hours after that till the patient was admitted in ICU. 83% of patients admitted belonged to 20-30 years age group

  • The SOFA score trend in the patients who recovered showed a significant decrease with time whereas the SOFA score trend in the patients who expired showed a significant increase with respect to time

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Summary

Introduction

Maternal deaths are defined by the WHO as the death of a woman while she is pregnant or within 42 days of termination of pregnancy, irrespective of the duration and the site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes. The Sequential Organ Failure Assessment (SOFA) score is one of the tools to evaluate the degree of organ failure in the patients leading to morbidity or mortality. Aims and Objectives: To validate that SOFA score can be used to know the prognosis of patients in obstetric ICU and to decide treatment . Materials and Methods: Organ failure was evaluated according to the maximum score for each one of its six components and the total SOFA score was calculated. Interpretation of the area under the ROC curve showed that the performance of the total maximum SOFA score was excellent (AUC 0.972; 95% CI: 0.917 to 0.995). Conclusion: Total SOFA score proved to be an effective tool for evaluating the severity and estimating prognosis in obstetric ICU.

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