Abstract
Na + transport studies in intestinal epithelial cells indicate that enterocytes from different regions of the small intestine differ in their response to actively transported sugars. 1. 1. Compared with sugar-free medium total Na + efflux rate constants from isolated rat jejunal cells were significantly increased when medium contained actively transported sugars, glucose and galactose, but not when medium contained fructose. 2. 2. In contrast total Na + efflux rate constants from isolated rat ileal cells did not respond to actively transported sugars, glucose and galactose. 3. 3. Similar results for the effect of actively transported sugars on Na + efflux were obtained for isolated rabbit jejunal and ileal epithelial cells. 4. 4. Passive Na + efflux rate constants for isolated jejunal and ileal enterocytes are not significantly different, indicating similar permeability characteristics.
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