Abstract
Diabetes mellitus (DM) is associated with an increased risk of stroke and cognitive impairment. The problem of preventing cerebral disorders in diabetes has not been solved. The review presents current data on the place and role of sodium-glucose cotransporters (SGLTs) in the brain, whose receptors play an important role in ischemia-reperfusion injury of the brain and neurodegenerative changes. Modern studies on the cerebroprotective effects of hypoglycemic drugs – SGLT inhibitors – are presented and summarized.
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