Abstract

Objective To investigate the sodium citrate regional anticoagulation in the hemoperfusion the clinical application.Methods 2009 November to 2011 November hemoperfusion in patients with retrospective case study,will be divided into two groups,the control group using conventional anticoagulation with heparin,sodium citrate group using sodium citrate in vitro anticoagulation,two groups were observed in patients with perfusion line thrombosis,platelet decrease,APTT extension the degree and incidence of bleeding.Results sodium citrate group perfusion line thrombosis,platelet decrease,APTT extended degree andbleeding incidence rate decreased significantly,the difference was statistically significant ( P ＜ 0.05).Conclusion sodium citrate anticoagulation can significantly reduce the blood perfusion of thrombosis and bleeding incidence. Key words: Hemoperfusion; Sodium citrate

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