Abstract

AbstractOne‐pot chemical synthesis of highly pure chalcone under mild conditions using biocompatible Na‐alginate biopolymer is reported. Several chalcone derivatives are prepared by magnetic stirring the equimolar quantities of the appropriate methyl ketone and aryl aldehyde with sodium alginate in ethanol under neutral conditions at room temperature. It is observed that in the presence of recyclable sodium alginate biocatalyst, highly pure chalcone with excellent yields in a very short time are obtained. The chalcone derivatives obtained are well characterized by UVDRS and FTIR techniques. The easily separable Na‐alginate biocatalyst acts as a Bronsted acid and may be reused up to five cycles.

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