Abstract

Objective To summarize the clinical features of global developmental delay (GDD) children, and to explore the relationship between severity of GDD and social-culture factors. Methods Sign the informed consent before enrollment. Collect clinical data in detail about 100 GDD children (GDD group) and 95 children with normal development (healthy control group), and analyze their regular clinical data, physical examination, intellectual disability test, electroencephalography (EEG) and cranial imaging test. Spearman rank correlation was used to analyze the differences of social and cultural factors between GDD group and healthy control group, such as maternal reproductive age, parental education level and family economic status. At the same time, we compared the lag degree of total developmental quotient and the degree of developmental retardation of five energy areas with the above factors. Results Significant associations were found between GDD and maternal/paternal education, economic level of family, but no sgnificant association was found between maternal age and GDD. And analysis in the relationship between severity of delay in all domains of the child's developmental status about language and social-culture factors, we only obtained the severity of delay in abilities about language is related with maternal education. Spearman rank correlation statistics explains that if there are the lower level of education with mothers, the delay of language domain will more severe (rs=-0.505, P<0.05). Conclusions Significant associations were found between GDD and maternal/paternal education, economic level of family. The higher maternal education was an important protective factor against risk of GDD. Improving the cognition of parents in child health care, early be diagnosed, early be intervened, is the most important for children with language development. Key words: Developmental disabilities; Socioeconomic factors; Child

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