Abstract

Interventions are urgently needed to reduce prescription opioid misuse risk factors, including anxiety and concomitant use of sedatives. However, only a limited number of randomized controlled opioid intervention trials have been conducted. We sought to determine whether an online behavior change/support community, compared to a control Facebook group, could reduce anxiety and opioid misuse among chronic pain patients. 51 high-risk non-cancer chronic pain patients were randomly assigned to either a Harnessing Online Peer Education (HOPE) peer-led online behavior change intervention or a control group (no peer leaders) on Facebook for 12 weeks. Inclusion criteria were: 18 years or older, a UCLA Health System patient, prescribed an opioid for non-cancer chronic pain between 3 and 12 months ago, and a score of ≥9 on the Current Opioid Misuse Measure (COMM) and/or concomitant use of benzodiazepines. Participation in the online community was voluntary. Patients completed baseline and follow-up assessments on Generalized Anxiety Disorder screener (GAD-7), COMM, and frequency of social media discussions about pain and opioid use. Compared to control group participants, intervention participants showed a baseline-to-follow-up decrease in anxiety, and more frequently used social media to discuss pain, prescription opioid use, coping strategies, places to seek help, and alternative therapies for pain. Both groups showed a baseline to follow-up decrease in COMM score. Preliminary results support the use an online community interventions as a low-cost tool to decrease risk for prescription opioid misuse and its complications.

Highlights

  • Prescription opioid misuse and abuse have reached epidemic proportions, nearly quadrupling from 2000 to 2014 [1]

  • We examined the potential peer-mediated effect on the intervention and found no differences in the Current Opioid Misuse Measure (COMM) and GAD-7 scores across the peer leaders

  • A 12-week intervention online support community for chronic pain patients at high risk for opioid misuse resulted in reduced anxiety and more frequent discussions about chronic pain and safe opioid management

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Summary

Introduction

Prescription opioid misuse and abuse have reached epidemic proportions, nearly quadrupling from 2000 to 2014 [1]. A 2013 study found that prescription opioids were the most frequently misused of all prescription medications, and accounted for more fatal overdoses than cocaine and heroin combined [2, 3]. Despite these complications, opioid prescribing for chronic pain skyrocketed during those years [4]. Interventions that successfully reduce anxiety and risk for prescription opioid misuse might have a important public health impact due to the large number of chronic opioid patients with comorbid mood disorders [6, 7]. Anxiety is a significant risk factor for opioid misuse and abuse, ; a limited number of randomized controlled opioid intervention trials have been conducted to date, with no studies showing improvements in anxiety [8]

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