Abstract
Relevance. The high prevalence of psoriasis among the population of the earth (0.1-7.0%), as well as the difficulty of its treatment, necessitate the development of new methods for its prevention and increasing the effectiveness of treatment.
 Objective. To study the peculiarities of the incidence of psoriasis in the population of the Zaporozhye region under the influence of unfavorable environmental factors.
 Methods. Under supervision in 2012, there were 5475 patients with psoriasis, of whom 2439 (44.5%) were women, 2731 (49.9%) were men and 305 (5.6%) were children. In 2013, there were 5635 patients with psoriasis, of whom 2504 (44.4%) were women, 2818 (50.0%) were men and 313 (5.6%) were children.
 Results. The highest levels of psoriasis in the Zaporozhye region are registered in Zaporozhye, Gulyaypol, Veselovsky, Kuibyshev, Primorsk and Vasilievsky districts. In these administrative units, the prevalence of psoriasis was within 269.6 - 513.8 cl. / 100 thousand, significantly higher than the average regional level (p <0.05), the prevalence of psoriasis in Zaporozhye (by 146.1 - 180.6 sl. / 100 thousand), in Gulyaypol district (by 96.1 - 141.9 cases / 100 thousand), and Veselovsky district (by 84.9 - 105.9 cases / 100 thousand).
 Conclusions: For the first time, a systematic approach to the analysis of the incidence of psoriasis with regard to environmental factors was used, in order to achieve stable remission in patients with active psoriasis, it is necessary to correct exogenous and endogenous trigger factors in order to minimize their effects.
Highlights
According to the International Federation of Psoriasis Associations, the prevalence of psoriasis in the world varies between 1.2-5% in general populations, with an average prevalence of about 3% [1]
The highest levels of psoriasis in the Zaporozhye region are registered in Zaporozhye, Gulyaypol, Veselovsky, Kuibyshev, Primorsk and Vasilievsky districts
The prevalence of psoriasis was within 269.6 - 513.8 cl. / 100 thousand, significantly higher than the average regional level (p
Summary
According to the International Federation of Psoriasis Associations, the prevalence of psoriasis in the world varies between 1.2-5% in general populations, with an average prevalence of about 3% [1]. Among 2-3% of the population of European countries there are various forms of psoriasis [2]. In other European countries, the prevalence of psoriasis does not exceed 6% of the total population: in Ireland - 5.5%, in Scotland - 4.8%, Spain - 3.7%, Sweden - 2.3%, Norway - 2.0%. In the US and Canada, these figures are 2.2% -4.6% and 4.7% respectively In the former USSR, the incidence of psoriasis among the general population was 2% [3]. The most common form of the disease is plaque psoriasis. Psoriasis in all its various clinical forms is one of the most common chronic inflammatory skin diseases. The socio-economic consequences of psoriasis are associated with chronization, a decline in labor productivity and a significant cost of treatment
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