Abstract

Journal of Paediatrics and Child HealthVolume 59, Issue 2 p. 414-414 Heads UpFree Access Social determinants of increased risk of cardiovascular disease in cancer survivors First published: 14 January 2023 https://doi.org/10.1111/jpc.16319 edited by Craig Mellis ([email protected]) AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Adolescent and young adult cancer survivors (aged 15–39 years) are at increased risk of developing cardiovascular disease. The causes of increased risk include drug toxicity, but the contribution of socio-demographic and modifiable factors is unknown. The current case–control study sought to fill these gaps.1 Researchers used self-reported data from the US National Health Interview Survey (2009–2018) to identify 4766 cancer survivors (≥2 years after diagnosis) and 47 660 age-matched and sex-matched controls.1 The data compared included socio-demographic factors (sex, race/ethnicity, income and education) and modifiable risk factors (diabetes, body mass index, smoking and physical activity). The rate of cardiovascular disease was significantly higher in survivors than in controls when analysed by sex, race/ethnicity, income, education, smoking status and physical activity. Poverty, defined as an annual household income <US$50 000, disproportionately increased the odds of cardiovascular disease. Any moderate-to-vigorous intensity physical activity compared to no regular physical activity lowered the odds of heart disease in survivors (odds ratio (OR) 0.61; 95% confidence interval (CI) 0.45–0.81) and in controls (OR 0.68; 95% CI 0.61–0.77). Thus, socio-demographic and modifiable risk factors increase the odds of cardiovascular disease in cancer survivors. Regular exercise is protective against heart disease both for cancer survivors and controls. Reference 1Berkman AM, Andersen CR, Roth ME, Gilchrist SC. Cardiovascular disease in adolescent and young adult cancer survivors: Impact of sociodemographic and modifiable risk factors. Cardiology 2023; 129: 450– 60. https://doi.org/10.1002/cncr.34505. Reviewer: David Isaacs, [email protected], Children's Hospital at Westmead, Sydney, New South Wales, Australia Volume59, Issue2February 2023Pages 414-414 ReferencesRelatedInformation

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