Abstract
Small intestinal bacterial overgrowth (SIBO) is characterized bynutrient malabsorption, associated with an excessive number of bacteria in the proximal smallintestine. Unfortunately, the diagnosis of bacterial overgrowth presents several difficulties andlimitations, and as yet there is not a widespread agreement on the best diagnostic test. SIBOoccurs when there are alterations in intestinal anatomy, gastrointestinal motility, or a lack ofgastric acid secretion. The true association between SIBO and irritable bowel syndrome andceliac disease remains uncertain. The treatment usually consists in the eradication of bacterialovergrowth with repeated courses of antimicrobials, nutritional support and when it is possible,the correction of underlying predisposing conditions (Rev Med Chile 2005; 133: 1361-70).(
Highlights
Small intestinal bacterial overgrowth (SIBO) is characterized by nutrient malabsorption, associated with an excessive number of bacteria in the proximal small intestine
celiac disease remains uncertain. The treatment usually consists in the eradication of bacterial overgrowth
Bacterial populations contaminating the upper gut in patients with small intestinal overgrowth syndrome
Summary
Rodrigo Quera P1,2, Eamonn MM Quigley[3], Ana María Madrid S1. Small intestinal bacterial overgrowth (SIBO) is characterized by nutrient malabsorption, associated with an excessive number of bacteria in the proximal small intestine. El SBI es usualmente definido como un recuento bacteriano >105 UFC/ml en el intestino delgado proximal[5,6]. Aunque se ha diagnosticado SBI usando test con (14C)D-xilosa, hasta en 35% de los sujetos senescentes sanos con hipoclorhidria, otros han descrito que el SBI puede ser una importante causa de malabsorción oculta en esta población[22]. Enfermedades con deterioro de la motilidad intestinal predisponen a un aumento de la flora bacteriana en el intestino delgado y son causas conocidas de SBI. Aplicando test espirado con lactulosa, Pimentel et al[19] encontraron que SOBRECRECIMIENTO BACTERIANO INTESTINAL - R Quera et al. Tabla 1. Prevalencia de sobrecrecimiento bacteriano intestinal (SBI) de acuerdo a las características de las poblaciones incluidas en los estudios y al método empleado en el diagnóstico
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