Abstract

Quality of life (QoL) data from randomized trials is lacking in older patients with metastatic colorectal cancer (mCRC). In the randomized NORDIC9-study, reduced-dose combination chemotherapy S1+oxaliplatin (SOx) showed superior efficacy compared to full-dose monotherapy S1 (Teysuno). Here, we hypothesized, that treatment with reduced-dose SOx does not result in inferior QoL and physical functioning compared to treatment with full-dose S1.

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