Abstract
Abstract This chapter summarizes several years' worth of experience discovering and using single nucleotide polymorphism (SNP) markers for a variety of projects including genetic mapping, positional cloning, evaluation of genetic diversity and genetic association analysis. Rather than giving a comprehensive review of literature, it focuses on conclusions and advice that may be helpful to those embarking on a new project involving SNP markers. The topics covered include: SNPs and other genetic markers; sources of SNP markers; genotyping methods; genetic mapping in segregating populations; fingerprinting; diversity analysis; genetic association mapping; SNPs in positional cloning; SNP markers in duplicated chromosome regions and in polyploids; outlook.
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