SNORES N DM2: STUDY ON OSA HIGH RISK PREVALENCE, SYMPTOMS, AND SLEEPINESS AMONG PATIENTS WITH UNCONTROLLED TYPE 2 DIABETES MELLITUS SEEN AT THE OUT-PATIENT DEPARTMENT IN A TERTIARY HOSPITAL

Abstract

SESSION TITLE: Advances Across the Diagnostic Spectrum in Sleep-Disordered Breathing SESSION TYPE: Original Investigations PRESENTED ON: October 18-21, 2020 PURPOSE: We determined the prevalence of patients at risk for OSA with uncontrolled T2DM at the OPD of UP -PGH from December 1, 2018 -February 28, 2019.We described the demographic characteristics of patients with uncontrolled T2DM and compared with high and low OSA risk, its association and correlation with quality of sleep. METHODS: Methodology:This is a prospective cross-sectional study among Uncontrolled T2DM.The questionnaires were Berlin Questionnaire (screen OSA–HR)and Epworth Sleepiness Score( level of sleepiness).Clinicodemographic profile and significant laboratory data were obtained. Descriptive statistics utilized. Chi- square test was used to compare categorical variables between patients with high vs.low OSA risk and to determine if an association exists between OSA-HR and sleep quality. RESULTS: 240 participants were included in the study. 88 males and 151 females. Over-all prevalence of OSA HR among patients with uncontrolled type 2DM is 58.33%. Majority of the OSA–HR(105 /140) were 46 years old and above. There is a significant association of tonsillar grade,malampati score, BMI, HGBA1C, hypercholesterolonemia, and Epworth sleepiness on OSA High risk. There is also substantial association with age, BMI, mallampati score, tonsillar grade, hypertension, asthma, HbA1c and hypercholesterelonemia on the level of sleepiness of OSA-HR. In conclusion, there is a high prevalence of high OSA- Risk among patients with uncontrolled DM . Factors associated with high OSA –Risk among uncontrolled diabetes mellitus include Hba1c, dyslipidemia, BMI , Mallampati Score , tonsillar grade and Epworth Score CONCLUSIONS: In conclusion, this study found that the prevalence rate of High risk OSA among type 2 uncontrolled Diabetes mellitus is 58.33% which is comparable to foreign literatures. Many patients with uncontrolled diabetes have higher risk for OSA. Factors associated with this higher risk include degree of sugar control (HbA1c), dyslipidemia, BMI, Mallampati score, tonsillar grading and Epworth scale. COPD, Asthma and uncontrolled hypertension are not correlated with OSA high risk but needs further investigation due to scarcity of cases recruited. CLINICAL IMPLICATIONS: A close follow-up and /or further definitive study (PSG) to confirm the results. It is recommended to increase the attention of our local health sector and department of Health in the provision of more sleep laboratories to correlate these results with a more definitive test for OSA. A creation of OSA club is recommended to follow-up those patients with High risk for OSA to prevent further complications and to provide a good glycemic control among T2DM. BQ and ESS plus sleep study should be incorporated as a screening test for patient with uncontrolled DISCLOSURES: No relevant relationships by Maria Lowella De Leon, source=Web Response no disclosure on file for Manuel Jorge; No relevant relationships by Anna Katrina Tojino, source=Web Response