Síndrome metabólico y enfermedad cardiovascular en la provincia de Cáceres: estudio SIMCERES

Abstract

Introduction and objectives Metabolic syndrome confers high cardiovascular risk in affected individuals. The objective of the SIMCERES study was to determine the prevalence of metabolic syndrome in patients with prior cardiovascular disease (ischemic heart disease, stroke and peripheral arterial disease), defined according to the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATP III) and International Diabetes Federation (IDF). Methods A population-based sample of 1498 persons aged more than 14 years old from the province of Caceres was randomly chosen using the healthcare identification code of primary care physicians. The determinations required to make a diagnosis of metabolic syndrome according to ATP-III and IDF criteria were performed and participants were questioned about their personal and family history of cardiovascular disease. Prior cardiovascular disease was detected in 204 individuals, representing 13.6% of the population. Results The prevalence of metabolic syndrome in persons with cardiovascular disease was 32.8% according to ATP-III criteria and 42.6% according to IDF criteria, with a mean age of 72.26±12.61 years (ATP-III criteria) and 70.99±13.05 years (IDF criteria). There were no differences between men and women in either of the two definitions. A statistically significant association was found between the presence of cardiovascular disease and metabolic syndrome, with both the ATP-III criteria (OR ATP-III: 3.2/95% CI 2.29–4.47) and the IDF criteria (OR IDF: 3.08/95%: 2.26–4.2) (p<0.0001). Conclusions Metabolic syndrome is highly prevalent in the population of the province of Caceres with prior cardiovascular disease. The prevalence of this syndrome increases with the age of the population and is the same in both sexes.