Abstract
The present report describes a case of Sezary syndrome in a canine with lymphadenomegaly, generalized erithroderma, intense pruritus and disseminated cutaneous nodules and plaques. Biopsy samples were taken from cutaneous nodules and plaques and were diagnosed epitheliotropic T cell cutaneous lymphoma by histology and immunohistochemical stain. Bone marrow cytology confirms leukemia. Diagnosis of Sezary syndrome was achieved through clinical, hematological, citopathological, histopathological and immunohistochemical findings. The patient was treated with Madison-Wisconsin chemotherapy protocol, but died after two mouths of treatment.
Highlights
The present report describes a case of Sezary syndrome in a canine with lymphadenomegaly, generalized erithroderma, intense pruritus and disseminated cutaneous nodules and plaques
Biopsy samples were taken from cutaneous nodules and plaques and were diagnosed epitheliotropic T cell cutaneous lymphoma by histology and immunohistochemical stain
The patient was treated with Madison-Wisconsin chemotherapy protocol, but died after two mouths of treatment
Summary
GHERNATI, I.; AUGER, C.; CHABANNE, L. et al Characterization of a canine long-term T-cell line established from a dog with sezary syndrome and producing retroviral particles. O linfoma cutâneo é uma neoplasia linfóide maligna que representa de 3 a 8% das neoplasias tegumentares em cães. O linfoma cutâneo epiteliotrópico manifesta-se sob três formas distintas: micose fungóide, síndrome de Sézary e reticulose pagetóide (Morrison, 1998).
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