Síndrome de Good y aplasia pura de la serie roja, reporte de un caso y revisión de la literatura: Report of one case

Camila Peña,Ana María Gray,María Elena Cabrera,Pilar Muñoz,Marvila Intriago

doi:10.4067/s0034-98872012000800013

Abstract

The association between Good's syndrome (hypogammaglobulinemia and thymoma) with pure red aplasia is very uncommon. We report a 70-year-old male, who had a thymoma excised nine years before. Afterwards, he suffered frequent respiratory infections, which were attributed to a humoral immunodeficiency. Nine years later, he developed a pure red cell aplasia. He received prednisone and cyclosporine, resulting in a progressive rise of hemoglobin level, after one month of treatment. The patient died shortly thereafter due to infection, complicating a domestic accident.

Highlights

The association between Good’s syndrome with pure red aplasia is very uncommon
We report a 70-year-old male, who had a thymoma excised nine years before
Afterwards, he suffered frequent respiratory infections, which were attributed to a humoral immunodeficiency

Summary

Introduction

The association between Good’s syndrome (hypogammaglobulinemia and thymoma) with pure red aplasia is very uncommon. La asociación con aplasia pura de la serie roja (APSR) es 5-10% y con inmunodeficiencia, denominada síndrome de Good (SG), alrededor de 5%. La APSR se ha asociado a infecciones virales, desórdenes autoinmune y neoplasias, siendo lo más frecuente la asociación con timoma.

Results

Conclusion