Abstract
Understanding how proteins fold is of extreme importance in biology. Increasing evidence show that protein folding is commonly initiated during synthesis while the nascent polypeptide is still bound to the ribosome. However, there is limited information on how this large macromolecule complex is involved in the whole process. Therefore, we aim to extend our understanding of co-translational folding. We make use of single molecule FRET (smFRET) to determine conformational changes on the protein by analyzing snapshots of the nascent chain at different lengths during synthesis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
