Abstract
Systemic blood pressure and tissue blood flow are regulated by the contractile status of smooth muscle cells located within the wall of small arteries and arterioles. One important signal that regulates arterial smooth muscle cell contractility is the intracellular calcium ion (Ca2+) concentration. Although Ca2+ was once considered to act only as a global intracellular signaling element, research performed over the past decade has revealed Ca2+ to act in a far more dynamic and versatile manner than previously thought possible.
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Schedule a callMore From: American Journal of Physiology-Heart and Circulatory Physiology
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