Abstract

Purpose. To compare the change of anterior corneal higher-order aberrations (HOAs) after laser in situ keratomileusis (LASIK), wavefront-guided LASIK with iris registration (WF-LASIK), femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE). Methods. In a prospective study, 82 eyes underwent LASIK, 119 eyes underwent WF-LASIK, 88 eyes underwent FS-LASIK, and 170 eyes underwent SMILE surgery. HOAs were measured with Pentacam device preoperatively and 6 months after surgery. The aberrations were described as Zernike polynomials, and analysis focused on total HOAs, spherical aberration (SA), horizontal coma, and vertical coma over 6 mm diameter central corneal zone. Results. Six months postoperatively, all procedures result in increase of anterior corneal total HOAs and SA. There were no significant differences in the induced HOAs between LASIK and FS-LASIK, while SMILE induced fewer total HOAs and SA compared with LASIK and FS-LASIK. Similarly, WF-LASIK also induced less total HOAs than LASIK and FS-LASIK, but only fewer SA than FS-LASIK (P < 0.05). No significant difference could be detected in the induced total HOAs and SA between SMILE and WF-LASIK, whereas SMILE induced more horizontal coma and vertical coma compared with WF-LASIK (P < 0.05). Conclusion. FS-LASIK and LASIK induced comparable anterior corneal HOAs. Compared to LASIK and FS-LASIK, both SMILE and WF-LASIK showed advantages in inducing less total HOAs. In addition, SMILE also possesses better ability to reduce the induction of SA in comparison with LASIK and FS-LASIK. However, SMILE induced more horizontal coma and vertical coma compared with WF-LASIK, indicating that the centration of SMILE procedure is probably less precise than WF-LASIK.

Highlights

  • Laser in situ keratomileusis (LASIK) was first introduced by Pallikaris et al in 1990 and has become presently the most common and effective refractive surgery to correct myopia, in which a stromal flap is created with a mechanical microkeratome, folded back, and repositioned

  • small incision lenticule extraction (SMILE) induced less total higher-order aberrations (HOAs) and spherical aberration (SA) compared with LASIK and FS-LASIK (P values were < 0.001 and 0.018, resp.)

  • Our results illustrated that the induced HOAs were significantly different among four treatment groups in favor of SMILE and WF-LASIK groups

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Summary

Introduction

Laser in situ keratomileusis (LASIK) was first introduced by Pallikaris et al in 1990 and has become presently the most common and effective refractive surgery to correct myopia, in which a stromal flap is created with a mechanical microkeratome, folded back, and repositioned. The main surgical step of this procedure is the flap creation [1], which induces corneal higher-order aberrations (HOAs) and may compromise postoperative visual quality [2]. In. 1999, wavefront-guided laser technology was introduced into the field of refractive surgery. 1999, wavefront-guided laser technology was introduced into the field of refractive surgery This improvement allows an optimized correction of spherocylindrical errors and of HOAs [5,6,7]. The induction of corneal HOAs has been reported [1, 8, 9]

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