Abstract
Recent events including the 11th September attacks in the USA and subsequent attacks using anthrax have firmly focused attention on the threat of biological warfare internationally. Ireland has been no exception to this global phenomenon and has already dealt with over 100 'anthrax' scares. However concern about other, more virulent biological threats continues to grow. Smallpox in particular has been highlighted as a potential biological warfare threat, given its high case fatality rate and its highly infectious nature. In this context it is useful to closely examine the Annual Reports of the Registrar Genera! for Ireland from almost a century ago to gain an insight into some of the issues that can be expected to emerge if the smallpox threat ever became real, or in the event of a Government campaign to vaccinate the population.
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