Abstract
In The Lancet, Ben Slotman and colleagues report the results of a phase 3 trial of thoracic radiotherapy for small-cell lung cancer. 1 Slotman BJ van Tinteren H Praag JO et al. Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trial. Lancet. 2014; (published online Sept 14.)http://dx.doi.org/10.1016/S0140-6736(14)61085-0 PubMed Google Scholar The trial is the most recent in a long line of studies showing that local radiotherapy benefits patients with small-cell lung cancer, a disease characterised by a bulky intrathoracic mass at presentation, a high propensity for metastasis, and high chemosensitivity, but with a poor prognosis. 2 van Meerbeeck JP Fennell DA De Ruysscher DK Small-cell lung cancer. Lancet. 2011; 378: 1741-1755 Summary Full Text Full Text PDF PubMed Scopus (690) Google Scholar Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trialThoracic radiotherapy in addition to prophylactic cranial irradiation should be considered for all patients with ES-SCLC who respond to chemotherapy. Full-Text PDF Open Access
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