Abstract
Following a simple and quick treatment based on dissolving the crude lipase of Candida rugosa in different percentages (v/v) of several polar organic solvents (methanol, ethanol, acetone, 1-propanol, 2-propanol, 1-butanol and 2-butanol), and a further dialysis, different preparations with enhanced activity and thermal stability were obtained. This improved catalytic behaviour was observed in aqueous media (more efficient triglyceride hydrolysis) as well as in anhydrous organic solvents (better enantioselectivity and/or yield in the esterification of R- and S-ketoprofen).Combination of this treatment with organic solvents with a correct control of water activity in the reaction media allowed a much better catalytic behaviour, dramatically increasing the reaction yield and the enantiodiscrimination ability in the esterification of S-ketoprofen vs. the R counterpart.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
