Abstract

Multiple Lymphomatous Polyposis (MLP) is characterized by multiple polyps with lymphoma invasion involving long segments of the Gastrointestinal (GI) tract. Most MLP are thought to represent Mantle Cell Lymphoma (MCL) of the GI tract. However, some follicular lymphomas, mucosa-associated lymphoid tissue lymphomas, and adult T-cell lymphomas [5] have been found to show a multiple polypoid appearance throughout long segments of the GI tract. We report a case with MLP associated with Small Lymphocytic Lymphoma (SLL). SLL in extranodal sites is difficult to diagnose and the clinical course is different from that of MCL. MCL has a more aggressive clinical course than Chronic Lymphocytic Leukemia or SLL (CLL/SLL). A median survival time of CLL/SLL is 7 to 10 years, while patients with MCL have a median survival of 3 years .

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