Abstract

AbstractThis chapter covers core curriculum topics relating to small intestinal disorders and malabsorption. This includes a discussion of key gut hormones involved in digestion and absorptive processes including with relevance for obesity. Questions on gastrointestinal neurotransmitters and transporters provide education in gut physiology. The protean presentations of several micronutrient deficiencies seen in clinical practice are discussed. Focus is given to the diagnosis, initial management and follow up of patients with coeliac disease and villous atrophy including later-onset complications such as enteropathy-associated T cell lymphoma. Also covered is the investigation of small intestinal motility disorders and the manifestations and management of functional abdominal conditions such as irritable bowel syndrome. Disorders of bile acid recirculation, microbial dysregulation including through acute infections, and key medications causing presentations with diarrhoea are incorporated in this chapter. Additional curriculum material regarding small intestinal disorders will also be covered in the mock examination chapter.

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