Abstract
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. It has a worse prognosis in younger women and most of them died within two years of diagnosis. We are reporting a unique case of SCCOHT in a 35 years old, nulliparous lady with primary infertility in which symptomatic hypercalcemia was a presenting feature of her cancer. She was completely healthy before third cycle of IVF. Within two months of her third IVF cycle, she developed SCCOHT with a very rapid and aggressive course of disease and fatal outcome. Patient died within one month of her first symptom presentation (3 months after IVF cycle).
Highlights
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is exceedingly rare tumor with very aggressive behavior and strikingly poor prognosis
Two third of these cases are associated with hypercalcemia
Symptoms of hypercalcemia, e.g., polyuria, polydipsia, anorexia, nausea, vomiting, constipation, muscle weakness, bone pain, decreased concentration, confusion, fatigue and coma was reported in only 2.5% of these patients.[2]
Summary
Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A rare case after In Vitro Fertilization. SUMMARY Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. It has a worse prognosis in younger women and most of them died within two years of diagnosis. We are reporting a unique case of SCCOHT in a 35 years old, nulliparous lady with primary infertility in which symptomatic hypercalcemia was a presenting feature of her cancer. She was completely healthy before third cycle of IVF.
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