Abstract
In order to clarify the effect of replacement of hydrogen oxide (H2O) by deuterium oxide (D2O) on the structure of phospholipid bilayers, we carried out small angle X-ray scattering (SAXS) measurements of dimyristoylphosphatidylglycerol (DMPG) bilayers in H2O and D2O. DMPG is an anionic phospholipid and spontaneously forms unilamellar vesicles in water. The obtained SAXS intensity curves were analyzed by using a structural model. The analysis showed that the replacement of H2O by D2O induces structural change at interfacial regions of the DMPG bilayers.
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