SMA - CLINICAL: P.80 Distribution of weight and height in children and adolescents with spinal muscular atrophy: An observational retrospective study in the United States

Abstract

Patients with spinal muscular atrophy (SMA) often show abnormalities in weight and height, which may be caused by bulbar dysfunction due to muscle weakness and complications of prolonged immobility; however, data on weight and height distribution in SMA is limited. This study evaluated the distribution of weight and height in US children and adolescents with infantile (Type 1) and later-onset SMA (Type 2/3) compared to reference values from healthy individuals (i.e. 50th percentiles from World Health Organization/Centers for Disease Control and Prevention charts).