Abstract

Slowing down DNA translocation speed in a nanopore is essential to realizing high resolution of individual bases. In this study, a uniform array of Platinum (Pt) and Silicon Oxide (SiOx) nanopillars created with Helium ion beam is introduced onto the trans side of Silicon Nitride layer to slow down DNA translocation. Both of Pt and SiOx nanopillars show a capability of great magnitude deceleration of dsDNA translocation. And the periodic space and diameter of nanopillars are precisely controlled, enabling further investigation of the interaction between pillars and the dsDNA. Pt and SiOx Plliars have different surface properties, hence we could explore the different interaction mechanism between Pt/SiOx Plliars and dsDNA.

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