Slow-growing gingival mass

Abstract

A 33-year-old woman presented with a slow growing palatal gingival mass. The clinical differential diagnosis included benign tumors and tumor-like lesions, including the pyogenic granuloma, peripheral giant cell granuloma, peripheral ossifying fibroma, giant cell fibroma, peripheral odontogenic tumors, and oral focal mucinosis. The lesion was excised and histopathological examination followed by immunohistochemical staining was carried out. The microscopic findings and the immunohistochemical reactivity was diagnostic for a nerve sheath myxoma. The clinical features, microscopic findings, immunohistochemistry, and the differential diagnosis including the relationship to the neurothekeoma are discussed.