Abstract
Obesity is associated with increased intra-abdominal pressure, impaired gastric emptying, and decreased lower esophageal sphincter (LES) pressure, all factors predisposing for gastroesophageal reflux disease (GERD).1 Furthermore, autonomic neuropathy in diabetes may increase the risk of GERD because of abnormal peristalsis and reduced LES pressure. Accordingly, patients with obesity and/or type 2 diabetes have a high prevalence of GERD and esophageal motility disorders. Weight loss reduces acid reflux.
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