Sleep study and pulmonary function in morbidly obese

Abstract

Obesity causes a series respiratory physiology and sleep changes. Its treatment aims to improve health and quality of life. The objective was evaluate pulmonary function and sleep in morbidly obese patients pre-bariatric surgery. The study had 38 patients recruited at two bariatric surgery services and referred to the Laboratório do Sono da Universidade Nove de Julho (Uninove), Sao Paulo, Brazil. The adopted criteria were: BMI between 40 kg/m 2 and 50 kg/m 2 and BMI between 35 kg/m 2 and 39.9 kg/m 2 with associated comorbidities. Mean age was 42 ± 10, the mean body mass index was 50.09 ± 7.64. The average waist circumference was 132.48 ± 11.07 and 134.31 ± 16.26; the neck circumference was 42.34 ± 2.08 and 44.48 ± 3.67, respectively for women and men. The maximum inspiratory pressures were 57.57 ± 18.93 and 60.6 ± 3.72 and 56.63 ± 16.69 maximal expiratory and 60 ± 18.52 for women and men, respectively. The rapid eye movement sleep presented a mean of 16.93 ± 13.61 and minimum oxy-hemoglobin saturation of 79.33 ± 10.26 during sleep. In 44.74% of the cases studied changes were observed in the Epworth Sleepiness Scale; and in 76.30% the presence of the syndrome of obstructive sleep apnea (OSA) was confirmed. We observed changes in maximum pressure ventilation in sleep structure associated with significant nocturnal desaturation of oxy-hemoglobin showing a high prevalence of OSA in morbidly obese patients. The Sleep Laboratory receives funding from the Universidade Nove de Julho (Brazil) and research projects approved by the Brazilian fostering agencies Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundaçao de Amparo a Pesquisa do Estado de São Paulo (FAPESP). LVFO received a grant from CNPq (Research Productivity modality - PQID, process number 307618/2010-2).