Abstract
Sleep and sleep spindle parameters were examined in 15 children with primary generalized spike-and-wave discharges at University Hospitals, Leuven, Belgium.
Highlights
Eyes were closed in 6 newborns, persistently in 3, during 10 seizures, all clonic and caused by HIE or cerebral infarction
Seizures were treated with phenobarbital in 50% of those with eyes open and in all 6 with eyes closed
When no simultaneous video EEG is available, persistent eye closure may be used to help distinguish nonepileptic from epileptic paroxysmal events in neonates with seizures, except in infants with HIE and those treated with phenobarbital
Summary
Sleep and sleep spindle parameters were examined in 15 children with primary generalized spike-and-wave discharges at University Hospitals, Leuven, Belgium. SIGNIFICANCE OF EYE OPENING OR CLOSURE IN NEONATAL SEIZURE DIAGNOSIS All archived neonatal seizures in the video database, at University Children's Hospital, Zurich, Switzerland, were reviewed and classified according to eyes open or closed during the event. Electroclinical seizures only were assessed, and electrographic seizures and clinical seizures without ictal EEG change were excluded.
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