Sleep Quality in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI).

Giulia Lorenzoni,Chiara Fraccaro,Danila Azzolina,Clara Minto,Sabino Iliceto,Dario Gregori,Giuseppe Tarantini,Caterina Zoccarato

doi:10.3390/ijerph18168889

Abstract

The present study aimed to analyze sleep quality and quality of Life (QoL) in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). It was conducted at the Interventional Cardiology Unit of the Department of Cardiac, Thoracic, Vascular Sciences and Public Health of the University of Padova on 27 adult patients who underwent TAVI via the transfemoral approach. Patients completed two validated instruments, i.e., the Pittsburgh Sleep Quality Index (PSQI) and the EuroQoL (EQ-5D-5L), on the day of discharge and one month after the hospital discharge. Twenty-seven patients were enrolled with a severe aortic stenosis diagnosis, treated with transfemoral TAVI procedure. The study population included seventeen poor sleepers and ten good sleepers with a median age of 81.92 years overall. The global PSQI evaluation revealed a small significant improvement at follow-up (p-value 0.007). Small positive changes were detected in the Self-care and Usual activity domains of the EQ-5D-5L and the EQ-VAS. No correlation was detected between EQ-5D-5L and sleep quality. The present study confirms the importance of sleep quality monitoring in patients who undergo TAVI procedure for aortic stenosis treatment.

Highlights

The wellbeing of patients is related to medical interventions, surgical procedures, or pharmacological treatments, but it is associated with the quality of daily activities such as eating, physical activity, or sleep [1]
The present study aims to fill this gap by analyzing patients’ perceived sleep quality and quality of Life (QoL) at discharge after the Transcatheter Aortic Valve Implantation (TAVI) procedure and one month after discharge
Adult patients diagnosed with aortic stenosis undergoing a TAVI procedure via the transfemoral approach were enrolled

Summary

Introduction

The wellbeing of patients is related to medical interventions, surgical procedures, or pharmacological treatments, but it is associated with the quality of daily activities such as eating, physical activity, or sleep [1]. Beyond scientific theories on the role of sleep on human homeostasis, this function’s importance is demonstrated by the health problems observed in acute or chronic sleep deprivation. These include negative consequences [3] on cardiovascular and immune systems, respiratory capacity, metabolic homeostasis, and cognitive ability. Large cohort studies have shown that sleep problems, e.g., short or long sleep duration, sleep arousal, insomnia, are associated with cardiovascular diseases onset and cardiovascular mortality [4,5]. It has been shown that patients with cardiovascular diseases are more likely to present with sleep problems, which are, in turn, associated with a poor prognosis [6]. Most of the studies investigating sleep problems in patients with cardiovascular diseases focus on heart failure and ischemic heart diseases

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Discussion

Conclusion