Abstract
BackgroundAlthough sleep is one of the most important health-related factors, the relationship between sleep duration and the incidence of cardiovascular events has not been fully described.MethodsThe present study comprised the 11 367 study subjects (4413 men and 6954 women) of the Jichi Medical School Cohort Study, a population-based prospective study. Baseline data were obtained by questionnaire and health examinations between April 1992 and July 1995 in 12 rural areas in Japan, and the main outcome measures were the incidence of cardiovascular diseases (stroke and myocardial infarction [MI]). Cox proportional hazards models were used to analyze the association between sleep duration and the incidence of cardiovascular events.ResultsA total of 481carciovascular events (255 men and 226 women) were observed during an average follow-up period of 10.7 years. After adjusting for age, systolic blood pressure, serum total cholesterol, body mass index, smoking habits, and alcohol drinking habits, the hazard ratios (95% confidence intervals) for the incidence of cardiovascular diseases for individuals sleeping less than 6 hours and 9 hours or longer were 2.14 (1.11–4.13) and 1.33 (0.93–1.92) in men, and 1.46 (0.70–3.04) and 1.28 (0.88–1.87) in women, respectively, relative to those who reported sleeping 7 to 7.9 hours per day.ConclusionsOur data indicate that men who sleep less than 6 hours a day have a higher risk of cardiovascular events than those sleeping 7 to 7.9 hours.
Highlights
Sleep is one of the most important factors contributing to health; sleep loss, long-term sleep deprivation, and alterations in sleep duration are common in modern society
We reported that men with short sleep duration and women with long sleep duration had an elevated risk of death.[7]
Systolic blood pressure (SBP), diastolic blood pressure (DBP), and serum total cholesterol level at baseline were positively associated with sleep duration in both sexes
Summary
Sleep is one of the most important factors contributing to health; sleep loss, long-term sleep deprivation, and alterations in sleep duration are common in modern society. The purpose of the present study was to examine whether sleep duration is associated with the incidence of cardiovascular diseases, ie, stroke and myocardial infarction (MI), in a Japanese population. After adjusting for age, systolic blood pressure, serum total cholesterol, body mass index, smoking habits, and alcohol drinking habits, the hazard ratios (95% confidence intervals) for the incidence of cardiovascular diseases for individuals sleeping less than 6 hours and 9 hours or longer were 2.14 (1.11–4.13) and 1.33 (0.93–1.92) in men, and 1.46 (0.70–3.04) and 1.28 (0.88–1.87) in women, respectively, relative to those who reported sleeping 7 to 7.9 hours per day. Conclusions: Our data indicate that men who sleep less than 6 hours a day have a higher risk of cardiovascular events than those sleeping 7 to 7.9 hours
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