Abstract

The review is devoted to the complex relationship between headache and sleep disorders. The shared neuroanatomical structures of the nervous system involved in pain perception and sleep are shown, and mechanisms of comorbidity between headaches and sleep disorders are considered. Various types of headaches in the continuum of the sleep–wake cycle are described. Both pharmacological and non-pharmacological approaches to treatment are examined in detail, with the biochemical basis of the drug action.

Highlights

  • Sleep is an integral part of our life and one of the basic needs of a person, and its disorders are a significant clinical problem

  • In the third revision of the International Classification of Headache Disorders (ICHD-3, 2018), sleep is mentioned 38 times [1], and headache in turn is listed in the International Classification of Sleep Disorders (ICSD) among the symptoms of sleep disorders [2]

  • The American Academy of Sleep Medicine considers headache associated with sleep one of the most common complaints of patients with headaches [3]

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Summary

Introduction

Sleep is an integral part of our life and one of the basic needs of a person, and its disorders are a significant clinical problem. Almost 50% of the population suffer from various types of sleep disorders. Sleep medicine studies various pathological phenomena of the sleep–wake cycle. Headaches are one of the most common medical problems In this regard, both phenomena have acquired the status of a global health burden. The American Academy of Sleep Medicine considers headache associated with sleep one of the most common complaints of patients with headaches (migraines or other types) [3]

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